Research and Grants

  1. Role of thrombospondin-1 methylation in glioblastoma multiforme

    Principal Investigator: Jean-Pierre Issa, MD

    Institute: Johns Hopkins Hospital

  2. Nonpathogenic polio recombinants as therapy for brain tumors

    Principal Investigator: Eckard Wimmer, PhD

    Institute: SUNY Stony Brook

  3. Identification of novel molecules that function in the PTEN/PI 3-kinase regulated signaling pathway in human glioblastoma cells

    Principal Investigator: Hong Sun, PhD

    Institute: Yale University

  4. Modulation of phosphoinositide-3-Oh kinase (P13-K) activation and glioma phenotype by signaling regulatory proteins

    Principal Investigator: Donald M. O'Rourke, MD

    Institute: University of Pennsylvania

  5. Immunotherapy of Malignant Gliomas Using Cytokine-Producing delta gamma-1 34.5 HSV

    Principal Investigator: Jacqueline N. Parker, Ph.D.

    Institute: University of Alabama, Birmingham

  6. Novel Hedgehog Pathway Antagonists as Potential Medulloblastoma Therapeutics

    Principal Investigator: James K. Chen, MD

    Institute: Stanford University

  7. Structural and biophysical investigation of plexin and the semaphorin system, as receptor-ligand complex implicated in the progression of brain tumors

    Principal Investigator: Dimitar Nikolov, PhD

    Institute: Memorial Sloan-Kettering Cancer Center

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